Biochemistry Research Topics

Biochemistry Research Topics

100 of The Best And Latest Biochemistry Research Topics


Biochemistry explores and investigates the different chemical reactions perpetrating the process that constitute life. It is a branch of science that combines multiple disciplines to understand biochemical processes in all life forms, from the simplest unicellular organisms to complex sentient species and even anomalies such as viruses & the like. Biochemistry dwells deep into the fundamental chemical processes of cells, tissues, organs & organisms. The other major research areas in the domain are the structure, function, production, and generation of biological molecules such as lipids, nucleic acids, carbohydrates, proteins, and the like.

Vast and intricate, biochemistry is a research-focused domain. Research and development in biochemistry engage researchers to investigate and learn more about different biological phenomena occurring at the molecular level.

This biochemistry assignment help guide lists out the top 100 biochemistry research topics today. So, let’s dive in right away. We also provide Bioinformatics Assignment Help to all the students who are searching for the same.

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100 Best And Latest Biochemistry Domains & Topics

We begin by looking at six of the most prominent biochemistry research areas.

  1. Signal Transduction

A significant research topic across top research universities all over, signal transduction shines light upon the processes that allow cells & biological systems to exchange signals & information.  

Transduction pathways enable and regulate diverse life-critical processes such as cell division, growth & development. Research in the field focuses upon:

  • Cell cycle regulation,

  • Morphogen signaling,

  • CNS signaling,

  • Regulation of blood & ion transportation,

  • Structure of the signaling molecules,

  1. Membranes & Transport Mechanisms

Biological mechanisms play a crucial role in the proper & continual functioning of cells & cellular systems. Dynamic and incredibly complicated, they vary and are generally made up of an ensemble of lipids and proteins that define the membrane’s permeability and other crucial functionalities.

Current research areas under the subject focus upon:

  • Cystic Fibrosis

  • Kidney Disease

  • Peptide and Protein Structure & Folding

  • Transmembrane Signalling

  • Membrane Biology & Ion Transportation

  • Mechanisms Behind Microbial Biofilms

  1. Gene Expression and Regulation

Genes are crucial to cells and cellular systems' proper functioning and resiliency. The ultimate developmental fate of any organism depends on specific patterns intrinsic in its genetic expression.

Specific programs investigate:

  • The cytoskeleton,

  • Signaling pathways,

  • Molecular mechanisms of cancer,

  • Proteins complexes & their structural biology,

  • Gene expression controlling,

  1. Protein Structure & Their Dynamics

The structure of proteins plays a significant role in their interactions and functioning. Advanced analytical techniques such as X-ray crystallography and electron microscopy have furthered research into the structural biology of proteins and how it affects different biomolecular interactions.

Major topics look into protein design & folding, interactions & folding, proteins & peptides in cellular membranes, protein aggregation, etc.

  1. Computational Biology

Computer-based approaches have led to drastic improvements in research & analysis. Big data, powerful analytics, and AI-based methods have now made it possible to record all the different types of components, processes, mechanisms, reactions, structures, and the like.

Research in this domain includes:

  • Genome sequencing and analysis

  • Modeling bio-molecular structures and processes

  • Investigating the dynamic nature of biochemical pathways

  • Bioinformatics

  • Digital analysis of the structure and functions of biomolecules

  1. Molecular Medicine

Biochemistry is central to the development of potent molecular drugs.

Research and investigation look into the mechanisms of processes, understand how drug reactions affect inter & intracellular biochemistry, and discover new therapeutic molecules after diligent screening & experiment.

Active research in the area focus upon:

  • Signaling Morphogen Pathways

  • Underlying molecular mechanisms in intracellular signaling

  • Structural Biology

  • Protein Functioning and their structural determinants

  • Protein Misfolding

The above six research domains are currently enjoying widespread prominence, with investigative endeavors & projects undertaken by top universities such as MIT, Harvard, Stanford, and the University of Toronto.

Next up, we dwell on 100 particular interesting & innovative research topics in biochemistry.

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100 Research Topics In Biochemistry For Theses & Dissertations

The following topics are the subjects of biochemistry research articles published in the Nature journal/magazine.

  1. A Modular Spring-Loaded Actuator for Membrane Protein Activation Through Mechanical Means

  2. Using confocal Raman microscopy to detect specific Intracellular Signature of the SARS-CoV-2 infection

  3. Platelet Proteome techniques to reveal the nature & feature of cell death, ant-viral response, and replication of viruses in SARS-CoV- 2 infection

  4. Different Trigger Factors that both hold and fold client proteins

  5. Alternative Approaches To Splicing As A Source of Phenotypic Diversity

  6. Next are some biochemistry research topics that have the subjects of numerous academic research projects across institutions.

  7. Exploring the aggregation of B-cell lymphocyte cell line in chickens and the governance of temperature sensitivity.

  8. The role of polyphosphate on the virulency of Erwinia caratovora

  9. Predicting protein dihedral angles using chemical shift information and associate data

  10. Discussions on the dissection of cellular & molecular functions of the latest blood-pressure controlling drugs

  11. Mechanisms and techniques for detecting mutations in fetuses.

  12. Investigating the role of food additives in the growth and development of bacteria in the human gut.

  13. Researching the chromosomal defects/mutations/abnormalities that lead to Down’s Syndrome.

  14. Evaluating & Exploring The Possibility & Processes For Removing & Replacing Disease-Causing Genes.

  15. Analyzing the key genetics and molecular nature of the causative gene that leads to muscular dystrophy.

  16. Research on plant respiration and glycolysis

  17. The current ethical and legal trends in biochemistry

  18. Understanding how the structure of molecules affects metabolic processes

  19. How does the human genome project affect contemporary human society? What effect will it have on the generations to come?

  20. Analysis of protein complexes that define DNA synthesis

  21. Understanding The Lattice Light-Sheet Microscopy

  22. Discussions and Research on Photosynthesis in genetically modified crops

  23. Investigating Biochemical Analysis Processes such as Ion-Mobility Mass Spectrometry, Selective, Plane Illumination, etc.

  24. Botany & Medicine

  25. Coordination of Cellular Sub-systems

  26. Magnesium- Understanding its physiological, clinical., and analytical perspectives.

  27. Role of Transcription In Biochemical Processes

  28. The Impact Of Supplementing Proteins & Vitamins In The Human Body

  29. Regulating The Initiation & Elongation of Transcription

  30. Looking Into ATP-Dependent Chromatin Modelling

  31. Understanding the properties of RNA polymerases in eukaryotic animals

  32. Experiments & Research for determining genome instability

  33. Exploring the RNA transcription process in-depth

  34. Role of Synthetase

  35. Discussions on the assembling and the regulation procedures during DNA forking.

  36. Regulation processes during RNA transcription

  37. Understanding Iron Binding In Proteins

  38. Advancements In High-Resolution Imaging and electron microscopy in biochemistry

  39. Processes for detecting cellular abnormalities

  40. Investigating the different factors affecting and regulating a cell cycle

  41. Processes and techniques for recording the atomic matrix of RNA

  42. Understanding the relationship between nuclear structure and chromatic structure

  43. Investigations into the biochemical properties of the Coronavirus

  44. The interconnections between cellular biology and molecular biology

  45. Research into indicators of metastatic bone diseases

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  1. Exploring the different factors that affect and disrupt signal transduction, neural pathways, and transcription factors

  2. Understanding Oncology at the cellular and molecular levels

  3. Vitamin C as a chief cancer-fighting agent

  4. Oxidative stress to eliminate cancer cells

  5. Developing effective biomarkers to determine how anti-cancer compounds work at the cellular level

  6. Understanding the different regulatory mechanisms in genetics

  7. Role of biochemical processes in the sustainment of life

  8. Investigating the effects of enzymes and catalysts in biological reactions

  9. Exploring and researching the factors that inhibit cell growth

  10. Analyzing The Complexity of RNA Transcription

  11. Research Into Platelets As Identifiers of Genetic Risk Factors

  12. Exploring the Process of Blood Clotting In Human Beings

  13. The Design of New Anti-Tumour Agents

  14. Experimental Approaches For Ascertaining Genomic Instability

  15. Biochemistry of Food Proteins

  16. Problem-Based Learning Approaches For Teaching Biochemistry

  17. Critical Study of Enzymes

  18. Role of Synthetase-tRNA complexes

  19. Understanding The Role of Peptides & Proteins In Cell Membranes

  20. Reviewing The Human Genome Mapping Project & Its Benefits

  21. Distinguishing & identifying the chemical compounds causing colon, pancreatic, and lung cancers

  22. Investigating the genetics of cancer molecules:  Gene expression and association studies

  23. The Effect of Genetics & Radiation Exposure On Brain Cancers

  24. Understanding The Chemical Properties Of Covid-19 vaccines and their vacations on males & females

  25. The Role of Biochemistry in Cell Motility

  26. Investigating how variant frequencies affect biochemical reactions

  27. Molecular genetic analysis of muscular dystrophy

  28. Molecular Analysis Processes For Investigating Gene Variations

  29. Studies For Determining The Binding Capabilities of Receptor Antigens

  30. Biochemical processes for detecting soft tissue sarcoma

  31. Investigating the atomic matrix of Ribonucleic acid

  32. The biochemical consequences of enzyme absence in the human body

  33. Investigating gene therapy

  34. Evaluating the physiochemical processes that occur in the Homo genus

  35. Current trends in molecular biochemistry

  36. Structural biology of the molecules affecting metabolic reactions

  37. Contribution of Biochemistry research In the development of computational Biology

  38. AI and Nanotechnology in Biochemistry & The development of molecular medicine

  39. Critical Studies & Examination of Autoimmunity & Inflammation

  40. Investigations Into the biosynthesis mechanisms of protein

  41. Stability, interactions, quantifications, and structural properties of proteins

  42. Understanding the roles of enzymatic and non-enzymatic proteins

  43. Studying the three-dimensional structure of immunoglobulins

  44. The Biochemistry of controlled mixed, liquid, and solid-state fermentation

  45. Research in nutritional biochemistry

  46. Investigating the biochemistry behind depression

  47. Analyzing DNA Synthesis Complexes

  48. Processes of Determining Mutations in the bacterial DNA

  49. Understanding the chemical composition of cells and how they enable different functions

  50. The biochemical factors leading to breast cancer.

That wraps up this write-up. So, go through this article in-depth and pick a research topic that interests you. And, if you need some professional biochemistry & bioinformatics assignment help or some guidance while writing your research papers, then has the brightest bunch of experts to help you out.

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